Acrylamide Toxicology

FAO/WHO Acrylamide in Food Network

Format	Author(s)	Title / Description	Date added	Details
	Adler, I.D.; Baumgartner, A.; Gonda, H.; Friedman, M.A.; Skerhut, M.	1-Aminobenzotriazole Inhibits Acrylamide-Induced Dominant Lethal Effects in Spermatids of Male Mice Report of a study to test whether acrylamide or glycidamide is responsible for clastogenicity in mouse spermatids. (more) Publication Month: March 2000	Jan 14, 2005
	Joint Institute for Food Safety and Applied Nutrition	2004 Acrylamide in Food Workshop: Update - Scientific Issues, Uncertainties, and Research Strategies Presentations and other materials from this workshop on acrylamide in foods held April 13-15, 2004 in Chicago, IL. (more) Event Dates: Tuesday, April 13, 2004 - Thursday, April 15, 2004 Publication Date: Tuesday, April 13, 2004	Apr 28, 2004
	Ghanayem, B.I.; Witt, K.L.; Kissling, G.E.; Tice, R.R.; Recio, L.	Absence of Acrylamide-induced Genotoxicity in CYP2E1-null Mice: Evidence Consistent with a Glycidamide-mediated Effect Report of a study on somatic cell damage in female wild-type and CYP2E1-null mice following administration of (more) Deadline: Monday, October 24, 2005 Publication Date: Saturday, October 15, 2005	Oct 24, 2005
	German Federal Institute for Risk Assessment	Acrylamid in Lebensmitteln - Erhöhtes Risiko für Diabetiker? [in German] This document discusses the metabolism of acrylamide and the significance of this to diabetics. Publication Date: Friday, July 25, 2003	Aug 10, 2004
	National Toxicology Program, Public Health Service, U.S. Department of Health and Human Services	Acrylamide Substance profile on acrylamide including information on carcinogenicity, properties, use, production, exposure, and regulations for acrylamide. (more) Publication Year: 2005	Aug 6, 2002
	Murray, Lindsay	Acrylamide This document gives effects, diagnosis, and management, physico-chemical properties, uses/circumstances of poisoning, (more)	Aug 6, 2002
	Air Toxics Website, Technology Transfer Network, Environmental Protection Agency	Acrylamide This fact sheet presents a hazard summary and information on uses, exposure routes, health effects, cancer risk, and physical properties of acrylamide. (more)	Sep 10, 2002
	Integrated Risk Information System, Environmental Protection Agency	Acrylamide (CASRN 79-06-1) Information and data on acrylamide from EPA's IRIS database. Includes Chronic Health Hazard Assessments for (more)	Aug 6, 2002
	International Agency for Research on Cancer	Acrylamide (Group 2A) This document describes exposure routes, carcinogenicity, and effects of acrylamide. Publication Year: 1994	Aug 6, 2002
	Rudén, C.	Acrylamide and Cancer Risk - Expert Risk Assessments and the Public Debate This report compares conclusions reached and primary data used for fourteen expert risk assessments on the (more) Publication Month: March 2004	Feb 17, 2004
	Atay, N. Zeynep; Çalgan, Dilek; Özakat, Emine; Varnali, Tereza	Acrylamide and Glycidamide Adducts of Guanine Short communication regarding a study on the adduct formation of acrylamide and glycidamide with Guanine. Access to (more) Deadline: Monday, August 29, 2005 Publication Date: Friday, September 2, 2005	Aug 29, 2005
	Baum, Matthias, et al.	Acrylamide and Glycidamide: Genotoxic Effects in V79-Cells and Human Blood Investigation of mutagenicity of acrylamide and its metabolite glycidamide. Access to the full text may require subscription or purchase. (more) Publication Date: Monday, February 7, 2005	Feb 15, 2005
	Godin, A.C., et al.	Acrylamide and N-methylolacrylamide Poisoning in a Herd of Charolais Crossbreed Cattle Abstract of a case study of the effects of acrylamide on seven beef cattle accidentally exposed while grazing. Publication Date: Saturday, December 14, 2002	Oct 21, 2003
	LoPachin, R. M.; Balaban, C. D.; Ross, J. F.	Acrylamide Axonopathy Revisited Report of a study of the brains and spinal cords of rats exposed to acrylamide in order to determine the primary site of acrylamide neurotoxicity. (more) Publication Date: Thursday, May 1, 2003	Oct 21, 2003
	Sega, G.A.; Alcota, R.P.; Tancongco, C.P.; Brimer, P.A.	Acrylamide Binding to the DNA and Protamine of Spermiogenic Stages in the Mouse and Its Relationship to Genetic Damage Abstract of a study of acrylamide binding in mouse spermatozoa. Publication Month: August 1989	Nov 17, 2004
	Ho, W.H.; Wang, S.M.; Yin, H.S.	Acrylamide Disturbs the Subcellular Distribution of GABAA Receptor in Brain Neurons Abstract of an article on a study of the effects of acrylamide on the GABA(A) receptor in brain neurons. Publication Year: 2002	Jan 20, 2004
	Wispriyono, B.; Matsuoka, M.; Igisu, H.	Acrylamide Does Not Cause Apparent Changes in Genetic Expression of Creatine Kinase in Rat Cerebellum Abstract of an article about a study of the effects of acrylamide on creatine kinase mRNA and protein level in rat cerebellum. (more) Publication Date: Monday, March 1, 2004	Mar 25, 2004
	Sega, G.A.; Generoso, E.E.; Brimer, P.A.	Acrylamide Exposure Induces a Delayed Unscheduled DNA Synthesis in Germ Cells of Male Mice That is Correlated with the Temporal Pattern of Adduct Formation in Testis DNA Abstract of a study of the induction of unscheduled DNA synthesis by acrylamide in male mice. Publication Year: 1990	Oct 19, 2004
	Naruszewicz, Marek; Zapolska-Downar, Danuta; Nowicka, Grazyna; Bukowska, Hanna; Siennicka, Aldona	Acrylamide from Processed Food: New Potential Risk Factor for Plaque Rupture Abstract from the 5th Annual Conference on Arteriosclerosis, Thrombosis, and Vascular Biology on a study of the (more) Publication Month: May 2004	Jul 27, 2004
	Joint Institute for Food Safety and Applied Nutrition	Acrylamide in Food Workshop: Scientific Issues, Uncertainties, and Research Strategies Proceedings from this meeting held October 28-30 in Chicago, IL, including reports and presentations from each (more) Event Dates: Monday, October 28, 2002 - Wednesday, October 30, 2002 Publication Date: Monday, October 28, 2002	Nov 21, 2002
	Rosen, Joseph D.	Acrylamide in Food: Is It a Real Threat to Public Health? "A Position Paper of the American Council on Science and Health." Discusses whether acrylamide is really a threat to (more) Publication Month: December 2002	Feb 12, 2003
	German BgVV (Federal Institute for Health Protection of Consumers and Veterinary Medicine)	Acrylamide in Foods - Serious Problem or Exaggerated Risk? Berlin, Germany: Report from this information seminar on acrylamide in foods. Topics include history and use of (more) Event Date: Thursday, August 29, 2002 Publication Month: August 2002	Aug 19, 2002
	Henry, Sara Hale; Koehler, Kathleen M.; Doerge, Daniel R.	Acrylamide in Foods: Toxicology, Epidemiology and Research Initiatives This presentation discusses studies and findings related to acrylamide in foods. It was presented at the 2003 (more) Publication Date: Thursday, June 12, 2003	Jun 19, 2003
	Vainio, Harri	Acrylamide in Heat-Processed Foods - A Carcinogen Looking for Human Cancer? This editorial reviews studies and data on the carcinogenic risk from acrylamide in foods and discusses data gaps and recommendations. (more) Publication Month: December 2003	Feb 10, 2004
	Health and Consumer Protection Directorate-General, European Commission	Acrylamide Information Base of Research Activities in the EU Directory of acrylamide activities in the EU. Information about study activities are given for studies in 10 areas: (more)	Mar 5, 2003
	LoPachin, Richard M.; Barber, David S.; He, Deke; Das, Soma	Acrylamide Inhibits Dopamine Uptake in Rat Striatal Synaptic Vesicles Report of a study of the effects of acrylamide exposure on dopamine transport into rat striatal synaptic vesicles. (more) Deadline: Monday, December 19, 2005 Publication Year: 2006	Dec 19, 2005
	Mucci, Lorelei A., et al.	Acrylamide Intake and Breast Cancer Risk in Swedish Women Research letter on a study of the association between dietary intake of acrylamide and increased risk of breast (more) Publication Date: Wednesday, March 16, 2005	Mar 28, 2005
	Calleman, C.J.; Bergmark, E.; Costa, L.G.	Acrylamide is Metabolized to Glycidamide in the Rat: Evidence from Hemoglobin Adduct Formation Abstract of a study on the formation of glycidamide from acrylamide. Publication Month: September 1990	Dec 22, 2004
	Lehning, E.J.; Balaban, C.D.; Ross, J.F.; Reid, M.A.; LoPachin, R.M.	Acrylamide Neuropathy: I. Spatiotemporal Characteristics of Nerve Cell Damage in Rat Cerebellum Report of a study on nerve somal, dendritic, axonal, and terminal degradation in the cerebellum of rats that were exposed to acrylamide. (more) Publication Month: September 2002	Oct 21, 2003
	Lehning, E.J.; Balaban, C.D.; Ross, J.F.; LoPachin, R.M.	Acrylamide Neuropathy: II. Spatiotemporal Characteristics of Nerve Cell Damage in Brainstem and Spinal Cord Report of a study on nerve cell body, dendrite, axon, and terminal degeneration in rat brainstems and spinal cords as a result of exposure to acrylamide. (more) Publication Month: January 2003	Oct 21, 2003
	Lehning, E.J.; Balaban, C.D.; Ross, J.F.; LoPachin, R.M.	Acrylamide Neuropathy: III. Spatiotemporal Characteristics of Nerve Cell Damage in Forebrain Report of a study of nerve cell body, dendrite, axon, and terminal argyrophilia in rat forebrain and nuclei as a result of exposure to acrylamide. (more) Publication Month: January 2003	Oct 21, 2003
	Wu, Qi, et al.	Acrylamide Stimulates Glutamine Uptake in Fischer 344 Rat Astrocytes by a Mechanism Involving Upregulation of the Amino Acid Transport System N Report of a study on the effects of acrylamide and histidine on the rate of 1-[G-3H]glutamine uptake in astrocyte (more) Deadline: Wednesday, October 19, 2005 Publication Year: 2005	Oct 19, 2005
	Abramsson-Zetterberg, Lilianne; Wong, Jennie; Ilbäck, Nils-Gunnar	Acrylamide Tissue Distribution and Genotoxic Effects in a Common Viral Infection in Mice Report of a study of the tissue distribution and genotoxic effects of [14C]acrylamide in female mice that were (more) Publication Date: Friday, July 1, 2005	May 9, 2005
		Acrylamide Toxicities and Food Safety: Session IV Summary and Research Needs From the 20th International Neurotoxicology Conference: Emerging Issues in Neurotoxicology, held November 18-21, 2002 (more) Publication Month: June 2004	Sep 15, 2004
	Sumner, Susan C.J., et al	Acrylamide: A Comparison of Metabolism and Hemoglobin Adducts in Rodents following Dermal, Intraperitoneal, Oral, or Inhalation Exposure Report of a study on the metabolism and hemoglobin adducts produced by acrylamide administered orally, dermally, (more) Publication Year: 2003	Oct 21, 2003
	Dearfield, Kerry L., et al.	Acrylamide: A Review of Its Genotoxicity and an Assessment of Heritable Genetic Risk Review of acrylamide genotoxicity studies and report of an assessment of the heritable genetic risk from acrylamide. (more) Publication Month: August 1995	Mar 12, 2004
	Sörgel, Fritz, et al.	Acrylamide: Increased Concentrations in Homemade Food and First Evidence of Its Variable Absorption from Food, Variable Metabolism and Placental and Breast Milk Transfer in Humans Editorial on a LC-MS/MS methodology developed to determine acrylamide levels in body fluids and foods. Includes (more) Publication Year: 2002	Jun 23, 2003
	Dearfield, K.L.; Abernathy, C.O.; Ottley, M.S.; Brantner, J.H.; Hayes, P.F.	Acrylamide: Its Metabolism, Developmental and Reproductive Effects, Genotoxicity, and Carcinogenicity Abstract of a review on acrylamide's carcinogenic, developmental, reproductive, and genotoxic effects and its (more) Publication Month: January 1988	Mar 12, 2004
	Mitka, Mike	Acrylamide-Food Link Questions Linger News article that discusses findings on the health effects of dietary acrylamide exposure. Access to the full text may require subscription or purchase. (more) Publication Date: Wednesday, July 28, 2004	Aug 3, 2004
	Park, Joungjoa, Lisa M. Kamendulis, Marvin A. Friedman, and James E. Klaunig	Acrylamide-Induced Cellular Transformation Abstract from a study of the ability of acrylamide to induce cellular transformation. The results of the study (more) Publication Year: 2002	Aug 28, 2002
	Yu, Sufang, et al.	Acrylamide-Induced Changes in the Neurofilament Protein of Rat Cerebrum Fractions Report of a study on changes in rat neurofilament proteins following treatment with acrylamide. Access to the full (more) Deadline: Monday, November 21, 2005 Publication Month: September 2005	Nov 21, 2005
	LoPachin, R.M., Jr.; Lehning, E.J.	Acrylamide-Induced Distal Axon Degeneration: A Proposed Mechanism of Action Abstract of a review article that discusses a mechanism for acrylamide axonopathy. Publication Year: 1994	Mar 17, 2004
	Nordin-Andersson, M.; Walum, E.; Kjellstrand, P.; Forsby, A.	Acrylamide-Induced Effects on General and Neurospecific Cellular Functions During Exposure and Recovery Abstract of a study on the effects of acrylamide on cell physiological and neurochemical functions. Publication Month: February 2003	Jan 21, 2004
	Yousef, M. I.; El-Demerdash, F. M.	Acrylamide-induced Oxidative Stress and Biochemical Perturbations in Rats Report of a study investigating the effects of different doses of acrylamide on some enzyme activities and lipid (more) Deadline: Wednesday, February 15, 2006 Publication Date: Wednesday, February 15, 2006	Feb 15, 2006
	Aschner, Michael; Cao, Cheng-Chen; Wu, Qi; Friedman, Marvin A.	Acute Effects of Acrylamide on Astrocyte Functions Report of a study on the effects of acrylamide on astrocyte function. Access to full text may require subscription. Publication Year: 2003	Jan 20, 2004
	Husoy,T.; Abramsson-Zetterberg, L.; Olstorn, H.B.; Paulsen, J.E.; Alexander, J.	Adenomatous polyposis coli Influences Micronuclei Induction by PhIP and Acrylamide in Mouse Erythrocytes Examination of impact of Apc on production of micronucleated erythrocytes after exposure to acrylamide, glycidamide, (more) Publication Date: Monday, February 7, 2005	Feb 16, 2005
	German Federal Institute for Risk Assessment	Aktivitäten von BgVV und BfR im Hinblick auf Acrylamid in Lebensmitteln [in German] This document discusses the actions of the BgVV and BfR with regards to acrylamide in foods, including measures (more) Publication Date: Wednesday, November 6, 2002	Aug 11, 2004
	Zamorano-Ponce, E., et al.	Anti-genotoxic Effect of Aloysia triphylla Infusion against Acrylamide-induced DNA Damage as Shown by the Comet Assay Technique Report of a study investigating the effects of an infusion of the leaves of a South American plant against genetic (more) Deadline: Wednesday, February 15, 2006 Publication Date: Tuesday, February 28, 2006	Feb 15, 2006
	Ling, Bing; Authier, Nicolas; Balayssac, David; Eschalier, Alain; Coudore, Francois	Assessment of Nociception in Acrylamide-induced Neuropathy in Rats Report of a study of behavioral modifications in rats given lower doses of acrylamide than those that cause motor (more) Deadline: Tuesday, January 17, 2006 Publication Date: Thursday, December 15, 2005	Jan 17, 2006
	Twaddle, Nathan C.; Churchwell, Mona I.; McDaniel, L. Patrice; Doerge, Daniel R.	Autoclave Sterilization Produces Acrylamide in Rodent Diets: Implications for Toxicity Testing Report of a study in which a method was developed for determining acrylamide levels and contamination in rodent (more) Publication Month: June 2004	Jun 29, 2004
	German Federal Institute for Risk Assessment	Bedeutung der Studie von